Rybelsus®

What is Rybelsus

Rybelsus is a medicine with the active ingredient semaglutide in tablet form from pharmaceutical company Novo Nordisk. It is registered for the treatment of adults with type 2 diabetes mellitus, when diet and exercise alone are not sufficient to control blood sugar. Within The Body Clinic, a doctor assesses during the consultation whether treatment with medication is suitable within a medical trajectory. More information about our medical approach can be found in our treatment program.

Semaglutide (oral)

Semaglutide is a GLP-1 receptor agonist. It stimulates insulin release when blood sugar rises and inhibits glucagon release. This leads to better blood sugar regulation. In oral form (Rybelsus), semaglutide is taken daily as a tablet. Its absorption in the body depends on the correct timing of intake.

Rybelsus for Type 2 Diabetes

Rybelsus is used as an adjunct to diet and exercise in adults with type 2 diabetes mellitus. The goal of treatment is to improve glycemic control and reduce the risk of complications.

Rybelsus price

The price is determined by the pharmacy and may vary by strength and dosage. Ask your pharmacy or health insurer for current information. Within The Body Clinic, a doctor assesses during the consultation whether treatment with medication is appropriate within a medical trajectory. More information can be found in our treatment program.

Who is Rybelsus suitable for?

Rybelsus may be prescribed to adults with: type 2 diabetes mellitus where diet and exercise alone are insufficient; possibly in combination with other diabetes medication, depending on the doctor's assessment. Rybelsus is not intended for type 1 diabetes or diabetic ketoacidosis.

Rybelsus prescription

Rybelsus is available by prescription only. A BIG-registered doctor assesses whether the medication is medically suitable and responsible for your situation. Within The Body Clinic, a doctor assesses during the consultation whether treatment with medication is suitable within a medical trajectory. More information can be found in our treatment program.

Rybelsus reimbursement

In certain cases, Rybelsus may be reimbursed for the treatment of type 2 diabetes mellitus. Conditions vary per health insurer and policy. Inquire with your pharmacy or insurer.

How Rybelsus works

Rybelsus contains semaglutide, which is similar to the body's own GLP-1 hormone. Summarized action:

• stimulates insulin release when blood sugar is high;
• inhibits glucagon release;
• helps lower blood sugar towards target values;
• supports the regulation of type 2 diabetes. The effect builds up gradually.

Ingredients in Rybelsus

Rybelsus is available in tablet form. According to the official product information, it contains: Active ingredient: semaglutide. Excipients: listed in the leaflet.

How to use Rybelsus?

• Always use as prescribed.
• Take the tablet once daily, on an empty stomach.
• At least 30 minutes before the first meal.
• With a small glass of water (max. 120 ml).
• Swallow tablet whole; do not break or chew.
• Wait 30 minutes before eating, drinking, or taking other medication.

Tips for use

• Take Rybelsus daily at the same time.
• Do not take a double dose if you miss a tablet.
• Do not stop without consulting your doctor.
• Consult if combining with other diabetes medication.

Rybelsus Side Effects

Possible side effects

• Very common: nausea, diarrhea.
• Common: vomiting, constipation, decreased appetite, abdominal pain.
• Occasional: flatulence, fatigue, dizziness.
• Rare: gallstones, kidney problems, allergic reaction.

Serious side effects – consult a doctor immediately

• severe abdominal pain (with or without vomiting);
• signs of gallbladder or liver problems;
• severe or prolonged nausea, vomiting, or diarrhea;
• swelling of the face, lips, tongue, or throat;
• sudden worsening vision (in retinopathy).
• Consult the leaflet for a complete overview.

Contraindications

Rybelsus should not be used:

• in case of allergy to semaglutide or excipients;
• in type 1 diabetes or diabetic ketoacidosis;
• in persons younger than 18 years.
• Use with caution in case of gastrointestinal problems or in combination with other diabetes medication.

Rybelsus during pregnancy or breastfeeding

Use during pregnancy or breastfeeding is not recommended. Always discuss your situation with your doctor before starting or continuing Rybelsus.