
Dissolving Fillers
Having fillers dissolved with Hyalase
From €250,-
Video about dissolving fillers

Is the result of a previous filler treatment not to your liking? Then Hyalase can be used to safely dissolve hyaluronic acid fillers. This treatment is also available at The Body Clinic with ultrasound guidance.

How does a Hyalase treatment work?
A Hyalase treatment safely dissolves unwanted hyaluronic acid fillers. We inject hyaluronidase, an enzyme that breaks down hyaluronic acid, which is then removed by the body. This happens within 24 to 48 hours. At The Body Clinic, we also offer ultrasound-guided dissolution, where we use ultrasound to accurately see where the filler is located.



Hyalase only dissolves hyaluronic acid fillers, not permanent fillers.

Why dissolve fillers?
Dissolving fillers with Hyalase can be considered when the result no longer meets your wishes or when a correction is needed. This may be the case when:
- You are dissatisfied with the result
- Too much filler has been injected
- There is an overcorrection
- You want to correct a previous filler treatment
Important: This treatment only works for temporary hyaluronic acid-based fillers and not for permanent fillers or other materials. The effect is usually visible within 24 to 48 hours.

Ultrasound-guided filler dissolution
At The Body Clinic, it is possible to dissolve fillers with ultrasound guidance in Groningen and Utrecht. With the help of ultrasound, the doctor can accurately see where the hyaluronic acid filler is located, allowing it to be dissolved precisely and safely. Advantages of ultrasound-guided filler dissolution:
- Precise localization of the fillers
- Targeted dissolution of existing fillers
- Treatment without the use of radiation
- Ultrasound-guided precision and control for the doctor
- Only suitable for hyaluronic acid fillers
Before and aftercare
Curious about the possibilities? Make an appointment.


Winner Best cosmetic clinic 2025
Our focus is always on care and quality. That is why we have been named Best cosmetic clinic 2025 by Injectablesbooking.nl and, with a 9.0 based on over 3,000 reviews on Kliniekervaringen.nl, have been one of the best-rated clinics in the Netherlands for years.
Get treated at The Body Clinic and give your face a subtle, fresh, and youthful appearance with natural results from our specialized doctors.

Free consultation
We believe it is important that you are well-informed before opting for a Hyalase treatment to dissolve fillers. That is why we always offer a free consultation with an experienced doctor. If you decide on a treatment, this can often be done immediately after the consultation, or you can schedule an appointment for a later time.
Clients rate us with a 9.0



"What a top doctor! I've tried many doctors, but Rosé is clear and honest, and what's truly amazing is that she gives injections and you feel NO pain."



"Quiet clinic, doctor Mirthe really takes the time to think along with you."



"Excellent result! After a long time of doubting, I finally decided to get fillers to straighten my nose, something that had bothered me for a very long time. I am incredibly happy with the result and the doctor's expertise!"



"Some time ago, I was treated by Randa, and I am extremely satisfied with the result and the service. The aftercare was truly excellent! Randa is a very pleasant employee who performs her work with passion, which made me feel incredibly comfortable! Definitely a great experience and highly recommended!"



"What a top doctor! I've tried many doctors, but Rosé is clear and honest, and what's truly amazing is that she gives injections and you feel NO pain."



"Quiet clinic, doctor Mirthe really takes the time to think along with you."

Safety of Hyalase
A Hyalase treatment to dissolve fillers is a safe and reliable treatment, provided it is performed by experienced doctors. As with any injectable treatment, we check in advance whether the treatment is safe and suitable for you. At The Body Clinic, all treatments are exclusively performed by BIG-registered cosmetic doctors.
Videos treatment
Find immediate answers to questions about treatments, costs, and recovery.
Yes, hyaluronic acid-based fillers can be dissolved with hyaluronidase (Hyalase). This endogenous substance dissolves the filler into small particles that can be removed by the body. It is important to know that only hyaluronic acid fillers can be dissolved with this method. Permanent fillers or fillers based on other substances cannot be removed with Hyalase.
Dissolving hyaluronic acid fillers can be done at least two weeks after the filler has been placed. This is an absolute minimum; in some cases, a longer waiting period may be necessary. Filler placement causes swelling. A doctor may advise you to wait longer (up to 6 weeks) before dissolving the filler. Often, the final result, completely free of all swelling, is only visible after this six-week period. Only then can you truly assess whether you are satisfied with the result or if you wish to have the filler dissolved.
The most precise way to dissolve hyaluronic acid fillers is via ultrasound guidance. The doctor dissolving the filler uses an ultrasound machine to precisely locate the filler, allowing for a more accurate procedure. This is especially valuable for hard-to-reach or misplaced fillers. At The Body Clinic, Dr. Rose Bischoff is the only doctor who dissolves fillers using ultrasound guidance. She works in Groningen and Utrecht. For regular Hyalase treatments, you can visit all locations.
When hyaluronic acid fillers have been placed incorrectly or in a difficult manner, making them hard to dissolve, you can opt to have your fillers dissolved under ultrasound guidance. The doctor dissolving the filler will use an ultrasound machine to precisely locate the filler, allowing for more accurate treatment. The ultrasound not only visualizes body tissues but also previously injected fillers. This enables the doctor to dissolve the filler very precisely, even in hard-to-reach areas.
The effect of Hyalase is rapid. The filler is usually largely or completely dissolved within 24 to 48 hours after injection. The hyaluronic acid is broken down and removed by the body. So, fairly quickly after the treatment, you will see the filler disappear and you will return to your original situation.
The process of dissolving fillers can be perceived as uncomfortable. The average pain score is 7 out of 10, which is higher than for filler injections. This is because Hyalase must be injected into the filler, which can cause more discomfort. If needed, an anesthetic cream can be used to enhance comfort.
Yes, after the filler has completely dissolved, you can choose to have another filler treatment at a later time. It is advisable to wait a few weeks after the filler has dissolved, allowing any swelling to completely subside and giving the doctor a clear understanding of your initial situation. During a consultation, the doctor can advise you on the appropriate timing for a new treatment.
No, Hyalase only works for hyaluronic acid-based fillers. These are temporary fillers that are naturally broken down by the body after 9-18 months. Permanent fillers or fillers based on other substances (such as calcium hydroxylapatite or poly-L-lactic acid) cannot be dissolved with Hyalase. At The Body Clinic, we exclusively use hyaluronic acid fillers, which means that all our filler treatments are reversible.
Yes, the result of dissolving fillers with Hyason (hyaluronidase) is generally visible quickly, but not always completely immediately. The speed at which you see the effect depends on various factors. Immediately after the injection with Hyason, the enzyme begins to break down the hyaluronic acid filler. Within a few hours to 24 hours, a clear reduction in volume is already visible. For smaller corrections or recent fillers, the effect may even be visible within 30 minutes to a few hours. For larger amounts of filler or older fillers, it can take 24 to 48 hours before the full effect is visible. It is important to know that temporary swelling can occur after dissolution due to the body's reaction to the enzyme. This makes it seem as if there is still volume present, while the filler has actually already dissolved. This swelling subsides within a few days. Therefore, a follow-up appointment is often scheduled after 1 to 2 weeks to assess the final result. If any filler remnants are still present, a second treatment may possibly take place.
For a treatment or free consultation, call our general number or make an appointment online. We are happy to help you.

























