The Washington University study revealed that its use may play a role in the treatment of conditions such as dementia. In this blog, we delve deeper into the study's findings and what this could mean for the future.
Please note: these and other weight-loss medications are currently only approved for the treatment of diabetes and obesity (BMI ≥ 27 with a weight-related condition, or BMI ≥ 30).
The Washington University Study
Scientists at Washington University investigated whether semaglutide (the active ingredient in Ozempic and Wegovy) can affect the development of dementia, specifically Alzheimer's disease. Dementia is considered 'type 3 diabetes' as patients with diabetes have an increased risk of developing dementia. The researchers analyzed medical data from a large group of patients with type 2 diabetes.
The results of this study were promising: patients using semaglutide had a significantly lower risk of Alzheimer's compared to people using other diabetes medications. The precise mechanisms causing this difference in risk are still unclear. The scientists suggest that the anti-inflammatory and metabolic properties of semaglutide might have a protective effect on the brain.
Future Outlook
The discoveries have led to growing interest in the medical community. Pharmaceutical companies are setting up various large-scale clinical trials to further investigate the effects of semaglutide on the brain. If these studies confirm Washington University's findings, this could mean a lot for the treatment of conditions like dementia.
While these prospects are hopeful, it is important to emphasize that semaglutide is not currently officially approved for use in dementia. The drug is prescribed as a treatment for diabetes and weight loss. Therefore, it is essential that follow-up research and clinical tests provide further insight into the safety and effectiveness of this application.
Conclusion
The NU.nl article sheds light on an unexpected potential application of semaglutide. Although the initial results are promising, it remains crucial to be cautious and await further studies that can confirm these results and safety in the context of dementia.
Nicolette studied Medicine at the University of Amsterdam. After conducting clinical research for several years into the development of diabetes in overweight individuals, she spent years guiding people with extreme obesity before and after gastric bypass surgery, with a strong focus on lifestyle coaching. With the advent of various weight-loss supporting medications, Nicolette also specialized in this area. Her combination of medical knowledge, scientific background, and years of practical experience enables her to find the most suitable and effective treatment for you. According to Nicolette, lifestyle changes are crucial in achieving and maintaining weight loss. Furthermore, a healthy lifestyle is not only important for weight reduction but also leads to an improvement in physical and mental health. "I believe that sustainable weight loss revolves around the right balance between medical support and lifestyle change. Medication can be a powerful aid, but real change occurs when we work together on habits that suit you and that you can maintain in the long term. Through my years of experience with people living with overweight and obesity, I know that every story is different. What works for one person may not work for another. That is why I take the time to listen to your situation and together find the most appropriate treatment – so that you not only lose weight but also feel truly better, both physically and mentally. Weight loss goes beyond a number on the scale. It's about energy, health, self-confidence, and quality of life. And you don't make that journey alone with us."
